Introduction of Professor He Shaoheng, "Changjiang Scholar" of Ministry of Education

1. Current position of Professor He Shaoheng

Professor He Shaoheng, born in 1957 in Santai County, Sichuan Province, has been a special professor of "Changjiang Scholars" of the Ministry of Education since 2001。He studied in the United Kingdom and the United States for 12 years。In 1999, he was a senior research fellow and doctoral supervisor at the University of Southampton。He is currently the executive director of the Institute of Integrative Medicine of Shenyang Medical College, the director of the Translational Medicine Research Center, the director of the Institute of Translational Medicine of Jinzhou Medical University, the deputy chairman of the Branch of Allergy of the Chinese Medical Association, and the leader of the Basic and Translational Medicine Group。He is mainly engaged in the research of the pathogenesis of allergic diseases and the research and development of diagnosis and treatment methods, and is a well-known expert in the international field of allergy. In 2014, he was approved by The State Council Government special allowance expert。

2. Major achievements of Professor He Shaoheng

He has published nearly 400 papers, of which 141 have been included by SCI, with a total impact factor of more than 400, and the articles have been cited more than 2700 times。Since returning to China in 2001, it has undertaken 12 national projects such as the "Twelfth Five-Year Plan" National Science and Technology Support Plan, key projects of the National Natural Science Foundation, 9 provincial key projects, and 1 major science and technology platform of Liaoning Province, with a total fund of more than 80 million yuan。Apply for 2 international invention patents;15 national invention patents were authorized and 12 were applied for.Obtained 6 national utility model patent authorization, 6 applications;Obtained 1 medical device production approval。He has won 1 first prize, 2 second prizes and 2 third prizes of provincial science and technology progress, ranking first。Editor-in-chief of 4 allergy monographs。A total of 55 postgraduate students, 19 doctoral students and 8 post-doctoral students have been trained。

3. Professor He Shaoheng's major scientific contributions

(1) Throughout history, the definition and diagnosis of diseases were mostly proposed by developed countries。The first annual China-Japan-South Korea Allergy Exchange in Tokyo in 2011，At home and abroad, it is the first to revise the definition of allergic diseases that has been used for nearly 40 years，Revise the original "allergic diseases are a group of diseases mediated by IgE" to "are a group of diseases mediated by mast cells/basophils"。It has been widely praised。

(2) Three hypotheses of "self-amplifying mechanism of mast cell degranulation signal", "Toll-like receptor activation of mast cells is the basis of endogenous asthma" and "self-amplifying mechanism of mast cell recruitment" were proposed for the first time, and the pathogenesis of allergy was discussed at the molecular level。

(3) A new experimental diagnostic procedure for allergic diseases was first proposed at home and abroad in 2012, and is currently being further confirmed。

(4) In 2011, the concept of the second generation of standardized allergen vaccine was first proposed at home and abroad, and the product will be higher than the current generation of the world's most widely used products (products such as Danish ALK company) to fill the domestic gap。

(5) Atopic patch test, food allergen patch test, common drug allergen patch test, and common metal contact allergen patch test were first developed at home and abroad，In China, we took the lead in developing a series of products such as photosensitive allergen patch test, cosmetic allergen patch test and non-cosmetic daily necessities allergen patch test，The application of patch test will be raised to a new level，Open up broad market prospects。

(6) At home and abroad to take the lead in the development of allergen-induced mast cell/basophil excitation test (in vitro diagnosis of allergic diseases "gold standard") kit，Combined with our second generation standardised allergen preparations，Will be the first to address the issue of allergen-induced mast cell/basophil excitation testing that has puzzled clinicians for nearly 40 years。